Abu Dhabi, Southampton - 21 night cruise

Day 1 Abu Dhabi, United Arab Emirates

Just a few decades ago, Abu Dhabi, the island capital of the United Arab Emirates, was a small fishing village with houses made of mud-brick and palm fronds. Today, as a result of revenue from oil, Abu Dhabi is one of the world's richest cities, with wide, tree-lined okulevards, lush green parks, gushing fountains and imposing skyscrapers. Somewhat of a dichotomy, Abu Dhabi is a combination of ultra-modern sophistication and Arab mystique, with friendly and hospitable people offering a warm welcome to visitors. Abu Dhabi's history originated in the 18th century, when, according to legend, a group of tribesmen pursuing a gazelle came upon a freshwater well which they named Abu Dhabi, or "Father of the Gazelle". In the 19th century, the first fort was built over this well by a sheikh of the Al-Nahyan dynasty. The fort's name is Al Husn Palace, also known as Old or White Fort, and it is one of the few buildings in Abu Dhabi that is more than 25 years old. Its whitewashed walls are eye-catching amid the backdrop of today's skyscrapers. Presently, it is home to the Cultural Foundation and serves as a documents centre. Abu Dhabi had little significance until the discovery of vast oil reserves in the late 1950s and early 1960s. In the years following, the city's economy and infrastructure developed rapidly and changed Abu Dhabi beyond recognition.

Day 3 Muscat, Oman

Oman's capital city is hemmed in on one side by spectacular jagged-peaked mountains and on the other by royal blue sea. The architecture is a traditional, sophisticated arabesque blend of white-washed, low-rise buildings surrounded by manicured palms, intricately designed domes set atop the minarets of the mosques, sand-colored villas, a surprising blend of modern art installations, like a giant incense burner that towers over the Corniche, and ancient forts set in the rocky hills. Though tradition abounds, from distinct, local cuisine to the widely worn national dress, the dishdasha, Muscat is a completely modern city, featuring opulent luxury hotels, international restaurants, excellent cellular and data service, sprawling shopping malls, pristine beaches, lively nightlife, world-class performing arts, and a highly educated population, most of whom speak English, Arabic, and often Hindi. Muscat is the ideal base for exploring other areas of the country since many of the most desirable destinations are within a few hours' drive.

Day 9 Safaga, Egypt

Port Safago has been undergoing a transformation, slowly metamorphosing into a holiday rsort. Like other cities on the Red Sea, the commercial port town sits close to great offshore dive sites. Unlike others, however, tourist development hasn't taken off in a meaningful way. But if the mass tourism in Hurghada is a turnoff, Safaga offers a small-scale and much more low-key alternative, though the best dive sites can still be seen on a day trip from Hurghada. Safaga is also the closest beach resort to Luxor and the Valley of the Kings, which lies 200 km (124 mi) to the southwest; when cruise ships offer land excursions to Luxor, they often do so through Safaga.

Day 12 Heraklion (Iraklion), Crete, Greece

Having been controlled by Arabic, Venetian and Ottoman empires over the years - it's no surprise that Heraklion is a diverse patchwork of exotic cultures and historical treasures. Celebrated as the birthplace of the Spanish Renaissance artist, El Greco, you can visit to explore the storied ruins of the Minoan empire's capital, and unearth the rich cultural treasures that Crete's bustling modern capital has to offer.

Day 14 Valletta, Malta

Malta's capital, the minicity of Valletta, has ornate palaces and museums protected by massive fortifications of honey-color limestone. Houses along the narrow streets have overhanging wooden balconies for people-watching from indoors. Generations ago they gave housebound women a window on the world of the street. The main entrance to town is through the City Gate (where all bus routes end), which leads onto Triq Repubblika (Republic Street), the spine of the grid-pattern city and the main shopping street. Triq Mercante (Merchant Street) parallels Repubblika to the east and is also good for strolling. From these two streets, cross streets descend toward the water; some are stepped. Valletta's compactness makes it ideal to explore on foot. City Gate and the upper part of Valletta are experiencing vast redevelopment that includes a new Parliament Building and open-air performance venue. The complex, completed mid-2013, has numerous pedestrian detours in place along with building noise and dust. Before setting out along Republic Street, stop at the tourist information office on Merchant Street for maps and brochures.

Day 16 Barcelona, Spain

The infinite variety of street life, the nooks and crannies of the medieval Barri Gòtic, the ceramic tile and stained glass of Art Nouveau facades, the art and music, the throb of street life, the food (ah, the food!)—one way or another, Barcelona will find a way to get your full attention. The capital of Catalonia is a banquet for the senses, with its beguiling mix of ancient and modern architecture, tempting cafés and markets, and sun-drenched Mediterranean beaches. A stroll along La Rambla and through waterfront Barceloneta, as well as a tour of Gaudí's majestic Sagrada Famíliaand his other unique creations, are part of a visit to Spain's second-largest city. Modern art museums and chic shops call for attention, too. Barcelona's vibe stays lively well into the night, when you can linger over regional wine and cuisine at buzzing tapas bars.

Day 18 Cádiz, Spain

Believed to be the oldest town on the Iberian Peninsula, the Andalusian port of Cádiz enjoys a stunning location at the edge of a six-mile promontory. The town itself, with 3,000 years of history, is characterised by pretty white houses with balconies often adorned with colourful flowers. As you wander around be sure to take a stroll through the sizeable Plaza de Espãna, with its large monument dedicated to the first Spanish constitution, which was signed here in 1812. Cádiz has two pleasant seafront promenades which boast fine views of the Atlantic Ocean, and has a lovely park, the Parque Genoves, located close to the sea with an open-air theatre and attractive palm garden. Also notable is the neo-Classical cathedral, capped by a golden dome.

Day 20 Vigo, Spain

Dating from Roman times, the Galician city of Vigo has a fine natural harbour and is renowned as the biggest fishing port in the world. It is also full of history - it was in this fjord-like quay that the English and Dutch defeated the French and Spanish fleets in 1702. Today, the attractive marinas stand in contrast to the industrialised areas of the city, while further exploration will reveal the characteristic 17th-century architecture and attractive countryside beyond. The charming Old Town is a delight, with its labyrinth of winding narrow streets and shaded squares. Nearby is the Cathedral city of Tui, and further to the north is the pilgrimage centre of Santiago de Compostela, which can be reached by car in approximately 1¼ hours.

Day 22 Southampton, England

Lying near the head of Southampton Water, a peninsula between the estuaries of the Rivers Test and Itchen, Southampton is Britain's largest cruise port. It has been one of England's major ports since the Middle Ages, when it exported wool and hides from the hinterland and imported wine from Bordeaux. The city suffered heavy damage during World War Two and as a result the centre has been extensively rebuilt, but there are still some interesting medieval buildings including the Bargate, one of the finest city gatehouses in England.