Day 1 Amsterdam, Netherlands

Amsterdam combines the unrivaled beauty of the 17th-century Golden Age city center with plenty of museums and art of the highest order, not to mention a remarkably laid-back atmosphere. It all comes together to make this one of the world's most appealing and offbeat metropolises in the world. Built on a latticework of concentric canals like an aquatic rainbow, Amsterdam is known as the City of Canals—but it's no Venice, content to live on moonlight serenades and former glory. Quite the contrary: on nearly every street here you'll find old and new side by side—quiet corners where time seems to be holding its breath next to streets like neon-lit Kalverstraat, and Red Light ladies strutting by the city's oldest church. Indeed, Amsterdam has as many lovely facets as a 40-carat diamond polished by one of the city's gem cutters. It's certainly a metropolis, but a rather small and very accessible one. Locals tend to refer to it as a big village, albeit one that happens to pack the cultural wallop of a major world destination. There are scores of concerts every day, numerous museums, summertime festivals, and, of course, a legendary year-round party scene. It's pretty much impossible to resist Amsterdam's charms. With 7,000 registered monuments, most of which began as the residences and warehouses of humble merchants, set on 160 man-made canals, and traversed by 1,500 or so bridges, Amsterdam has the largest historical inner city in Europe. Its famous circle of waterways, the grachtengordel, was a 17th-century urban expansion plan for the rich and is a lasting testament to the city's Golden Age. This town is endearing because of its kinder, gentler nature—but a reputation for championing sex, drugs, and rock 'n' roll does not alone account for Amsterdam's being one of the most popular destinations in Europe: consider that within a single square mile the city harbors some of the greatest achievements in Western art, from Rembrandt to Van Gogh. Not to mention that this is one of Europe's great walking cities, with so many of its treasures in the untouted details: tiny alleyways barely visible on the map, hidden garden courtyards, shop windows, floating houseboats, hidden hofjes(courtyards with almshouses), sudden vistas of church spires, and gabled roofs that look like so many unframed paintings. And don't forget that the joy lies in details: elaborate gables and witty gable stones denoting the trade of a previous owner. Keep in mind that those XXX symbols you see all over town are not a mark of the city's triple-X reputation. They're part of Amsterdam's official coat of arms—three St. Andrew's crosses, believed to represent the three dangers that have traditionally plagued the city: flood, fire, and pestilence. The coat's motto ("Valiant, determined, compassionate") was introduced in 1947 by Queen Wilhelmina in remembrance of the 1941 February Strike in Amsterdam—the first time in Europe that non-Jewish people protested against the persecution of Jews by the Nazi regime.

Day 4 Akureyri, Iceland

Akureyri, called the Capital of the North is the second largest urban area in Iceland, and a lively one at that. Hemmed by the 60-km (37-mile) long Eyjafjörður, Akureyri is sheltered from the ocean winds and embraced by mountains on three sides. Late 19th-century wooden houses impart a sense of history, and the twin spires of a modern Lutheran church rising on a green hill near the waterfront, provide a focal point. To the south of Akureyri is the pyramid-shape rhyolite mountain Súlur. Beyond it is Kerling, the highest peak in Eyjafjörður District.

Day 5 Isafjørdur, Iceland

Two colossal terraces of sheer rock stand either side of this extraordinarily located town - which rides a jutting spit onto an immensity of black fjord water. Surprisingly, considering the remoteness of its location and its compact size, Isafjordur is a modern and lively place to visit, offering a great choice of cafes and delicious restaurants – which are well stocked to impress visitors. The town is a perfectly located base for adventures amongst Iceland's fantastic wilderness - with skiing, hiking and water-sports popular pursuits among visitors.

Day 6 Reykjavík, Iceland

Sprawling Reykjavík, the nation's nerve center and government seat, is home to half the island's population. On a bay overlooked by proud Mt. Esja (pronounced eh-shyuh), with its ever-changing hues, Reykjavík presents a colorful sight, its concrete houses painted in light colors and topped by vibrant red, blue, and green roofs. In contrast to the almost treeless countryside, Reykjavík has many tall, native birches, rowans, and willows, as well as imported aspen, pines, and spruces.Reykjavík's name comes from the Icelandic words for smoke, reykur, and bay, vík. In AD 874, Norseman Ingólfur Arnarson saw Iceland rising out of the misty sea and came ashore at a bay eerily shrouded with plumes of steam from nearby hot springs. Today most of the houses in Reykjavík are heated by near-boiling water from the hot springs. Natural heating avoids air pollution; there's no smoke around. You may notice, however, that the hot water brings a slight sulfur smell to the bathroom.Prices are easily on a par with other major European cities. A practical option is to purchase a Reykjavík City Card at the Tourist Information Center or at the Reykjavík Youth Hostel. This card permits unlimited bus usage and admission to any of the city's seven pools, the Family Park and Zoo, and city museums. The cards are valid for one (ISK 3,300), two (ISK 4,400), or three days (ISK 4,900), and they pay for themselves after three or four uses a day. Even lacking the City Card, paying admission (ISK 500, or ISK 250 for seniors and people with disabilities) to one of the city art museums (Hafnarhús, Kjarvalsstaðir, or Ásmundarsafn) gets you free same-day admission to the other two.

Day 9 Qaqortoq (Julianehaab), Greenland

The largest town in southern Greenland, Qaqortoq has been inhabited since prehistoric times. Upon arrival in this charming southern Greenland enclave, it's easy to see why. Qaqortoq rises quite steeply over the fjord system around the city, offering breath-taking panoramic vistas of the surrounding mountains, deep, blue sea, Lake Tasersuag, icebergs in the bay, and pastoral backcountry. Although the earliest signs of ancient civilization in Qaqortoq date back 4,300 years, Qaqortoq is known to have been inhabited by Norse and Inuit settlers in the 10th and 12th centuries, and the present-day town was founded in 1774. In the years since, Qaqortoq has evolved into a seaport and trading hub for fish and shrimp processing, tanning, fur production, and ship maintenance and repair.

Day 11 Nuuk (Godthaab), Greenland

Nuuk, meaning “the cape”, was Greenland's first town (1728). Started as a fort and later mission and trading post some 240 kilometers south of the Arctic Circle, it is the current capital. Almost 30% of Greenland's population lives in the town. Not only does Nuuk have great natural beauty in its vicinity, but there are Inuit ruins, Hans Egede's home, the parliament, and the Church of our Saviour as well. The Greenlandic National Museum has an outstanding collection of Greenlandic traditional dresses, as well as the famous Qilakitsoq mummies. The Katuaq Cultural Center's building was inspired by the undulating Northern Lights and can house 10% of Nuuk's inhabitants.

Day 14 Charlottetown, Prince Edward Island, Canada

Designated as the Island capital in 1765, Charlottetown is both PEI's oldest and largest urban center. However, since the whole "metropolitan" area only has a population of about 65,000, a pleasing small-town atmosphere remains. The city is a winner appearance-wise as well. Peppered with gingerbread-clad homes, converted warehouses, striking churches, and monumental government buildings, Charlottetown's core seems relatively unchanged from its 19th-century heyday when it hosted the conference that led to the formation of Canada. The city is understandably proud of its role as the "Birthplace of Confederation" and, in summer, downtown streets are dotted with people dressed as personages from the past who'll regale you with tales about the Confederation debate.

Day 15 Sydney, Nova Scotia, Canada

If you come directly to Cape Breton via plane, ferry, or cruise ship, Sydney is where you'll land. If you're seeking anything resembling an urban experience, it's also where you'll want to stay: after all, this is the island's sole city. Admittedly, it is not the booming center it was a century ago when the continent's largest steel plant was located here (that era is evoked in Fall on Your Knees, an Oprah Book Club pick penned by Cape Bretoner Anne-Marie MacDonald). However, Sydney has a revitalized waterfront and smattering of Loyalist-era buildings that appeal to visitors. Moreover, it offers convenient access to popular attractions in the region—like the Miner's Museum in nearby Glace Bay (named for the glace, or ice, that filled its harbor in winter), the Fortress at Louisbourg, and beautiful Bras d'Or Lake.

Day 17 Boston, Massachusetts, United States

There's history and culture around every bend in Boston—skyscrapers nestle next to historic hotels while modern marketplaces line the antique cobblestone streets. But to Bostonians, living in a city that blends yesterday and today is just another day in beloved Beantown.