Day 1 Civitavecchia, Italy

Italy's vibrant capital lives in the present, but no other city on earth evokes its past so powerfully. For over 2,500 years, emperors, popes, artists, and common citizens have left their mark here. Archaeological remains from ancient Rome, art-stuffed churches, and the treasures of Vatican City vie for your attention, but Rome is also a wonderful place to practice the Italian-perfected il dolce far niente, the sweet art of idleness. Your most memorable experiences may include sitting at a caffè in the Campo de' Fiori or strolling in a beguiling piazza.

Day 2 Salerno, Italy

Salerno is an Italian city located on the Gulf of Salerno. Famous for being home to the first medical university, Salerno is a great destination for anyone looking for gorgeous sea views filled with sunshine and Italian food.

Day 3 Messina, Italy

Home to the Museo Regionale of Messina, known for featuring two of Caravaggio's paintings, the city is also famous for having been the capital of the ancient kingdom of Sicily.

Day 4 Valletta, Malta

Malta's capital, the minicity of Valletta, has ornate palaces and museums protected by massive fortifications of honey-color limestone. Houses along the narrow streets have overhanging wooden balconies for people-watching from indoors. Generations ago they gave housebound women a window on the world of the street. The main entrance to town is through the City Gate (where all bus routes end), which leads onto Triq Repubblika (Republic Street), the spine of the grid-pattern city and the main shopping street. Triq Mercante (Merchant Street) parallels Repubblika to the east and is also good for strolling. From these two streets, cross streets descend toward the water; some are stepped. Valletta's compactness makes it ideal to explore on foot. City Gate and the upper part of Valletta are experiencing vast redevelopment that includes a new Parliament Building and open-air performance venue. The complex, completed mid-2013, has numerous pedestrian detours in place along with building noise and dust. Before setting out along Republic Street, stop at the tourist information office on Merchant Street for maps and brochures.

Day 5 La Goulette, Tunisia

Day 6 Cagliari, Italy

Known in Sardinia as Casteddu, the island's capital has steep streets and impressive Italianate architecture, from modern to medieval. This city of nearly 160,000 people is characterized by a busy commercial center and waterfront with broad avenues and arched arcades, as well as by the typically narrow streets of the old hilltop citadel (called, simply, “Castello”). The Museo Archeologico makes a good starting point to a visit. The imposing Bastione di Saint Remy and Mercato di San Benedetto (one of the best fish markets in Italy) are both musts.

Day 8 Alicante, Spain

The provincial capital of the Valencian Community serves as a gateway to the huge influx of tourists that flock to the Costa Blanca resorts every year. Alicante is popular with holidaymakers who arrive for the warm, Mediterranean climate and seemingly endless golden beaches. However, there is much more to this city than sand and sun. With a picturesque waterfront, a hugely impressive castle, buzzing nightlife and a rich, complex history, Alicante is a fascinating destination all year round.

Day 9 Cartagena, Spain

A Mediterranean city and naval station located in the Region of Murcia, southeastern Spain, Cartagena's sheltered bay has attracted sailors for centuries. The Carthaginians founded the city in 223BC and named it Cartago Nova; it later became a prosperous Roman colony, and a Byzantine trading centre. The city has been the main Spanish Mediterranean naval base since the reign of King Philip II, and is still surrounded by walls built during this period. Cartagena's importance grew with the arrival of the Spanish Bourbons in the 18th century, when the Navidad Fortress was constructed to protect the harbour. In recent years, traces of the city's fascinating past have been brought to light: a well-preserved Roman Theatre was discovered in 1988, and this has now been restored and opened to the public. During your free time, you may like to take a mini-cruise around Cartagena's historic harbour: these operate several times a day, take approximately 40 minutes and do not need to be booked in advance. Full details will be available at the port.

Day 10 Melilla, Spain

The autonomous city of Melilla is a Spanish enclave located on the Mediterranean Rif coast of North Africa, bordering Morocco. Its chequered past embraced periods of Phoenician, Punic, Roman and Byzantine rule before it was conquered by Spain in 1497. The latter part of the 19th century and the first quarter of the 20th century saw hostilities between Rif berbers and the Spanish, with the latter finally reinstating their control in 1927. The city was used by General Franco as one of the staging points for the rebellion of 1936. As part of the Spanish protectorate, Melilla developed the architectural style of 'Modernisme', the Catalan version of Art Nouveau, and boasts the second most important concentration of Modernist works in Spain, after Barcelona.

Day 11 Málaga, Spain

As you sail into Malaga you will notice what an idyllic setting the city enjoys on the famous Costa del Sol. To the east of this provincial capital, the coast along the region of La Axarqua is scattered with villages, farmland and sleepy fishing hamlets - the epitome of traditional rural Spain. To the west stretches a continuous city where the razzmatazz and bustle creates a colourful contrast that is easily recognisable as the Costa del Sol. Surrounding the region, the Penibéetica Mountains provide an attractive backdrop overlooking the lower terraced slopes which yield olives and almonds. This spectacular mountain chain shelters the province from cold northerly winds, giving it a reputation as a therapeutic and exotic place in which to escape from cold northern climes. Malaga is also the gateway to many of Andalusia's enchanting historic villages, towns and cities.

Day 12 Cádiz, Spain

Believed to be the oldest town on the Iberian Peninsula, the Andalusian port of Cádiz enjoys a stunning location at the edge of a six-mile promontory. The town itself, with 3,000 years of history, is characterised by pretty white houses with balconies often adorned with colourful flowers. As you wander around be sure to take a stroll through the sizeable Plaza de Espãna, with its large monument dedicated to the first Spanish constitution, which was signed here in 1812. Cádiz has two pleasant seafront promenades which boast fine views of the Atlantic Ocean, and has a lovely park, the Parque Genoves, located close to the sea with an open-air theatre and attractive palm garden. Also notable is the neo-Classical cathedral, capped by a golden dome.

Day 14 Lisbon, Portugal

Set on seven hills on the banks of the River Tagus, Lisbon has been the capital of Portugal since the 13th century. It is a city famous for its majestic architecture, old wooden trams, Moorish features and more than twenty centuries of history. Following disastrous earthquakes in the 18th century, Lisbon was rebuilt by the Marques de Pombal who created an elegant city with wide boulevards and a great riverfront and square, Praça do Comércio. Today there are distinct modern and ancient sections, combining great shopping with culture and sightseeing in the Old Town, built on the city's terraced hillsides. The distance between the ship and your tour vehicle may vary. This distance is not included in the excursion grades.

Day 15 Portimão, Portugal

Portimão is a major fishing port, and significant investment has been poured into transforming it into an attractive cruise port as well. The city itself is spacious and has several good shopping streets—though sadly many of the more traditional retailers have closed in the wake of the global economic crisis. There is also a lovely riverside area that just begs to be strolled (lots of the coastal cruises depart from here). Don't leave without stopping for an alfresco lunch at the Doca da Sardinha ("sardine dock") between the old bridge and the railway bridge. You can sit at one of many inexpensive establishments, eating charcoal-grilled sardines (a local specialty) accompanied by chewy fresh bread, simple salads, and local wine.

Day 17 Funchal, Madeira, Portugal

Formed by a volcanic eruption, Madeira lies in the Gulf Stream, about 500 miles due west of Casablanca. Discovered by Portuguese explorer João Gonçalves Zarco in 1419, this beautiful island became part of Portugal's vast empire and was named for the dense forest which cloaked it - 'Madeira' means 'wood' in Portuguese. Sugar plantations first brought wealth here, and when King Charles II of England granted an exclusive franchise to sell wine to England and its colonies, many British emigrants were drawn to the capital, Funchal. Today's travellers come to Madeira for the varied and luxuriant scenery, from mountain slopes covered with vines to picturesque villages and a profusion of wild flowers. The natural beauty of the island has earned it many pseudonyms such as ‘The Floating Garden of the Atlantic', 'The Island of Eternal Springtime' and ‘God's Botanical Gardens' and our selection of excursions aim to show you why.

Day 18 Santa Cruz de Tenerife, Spain

The largest of the Canary Islands, Tenerife is a beautiful and scenic island which enjoys year-round sunshine and is dominated by Mount Teide. The mountain range runs through the centre of the island, with fertile valleys on the northern side. In the central part of the range is the gigantic natural crater of the Cañadas del Teide, about 14 miles in diameter. Santa Cruz, the island's pretty capital, was originally a small fishing village but has now grown into a modern city, and also contains 16th-century civic buildings and ornate private mansions. Near the pier is the Santa Cruz Palmetum, a Botanical Garden covering an area of 29 acres, specialising in palms.

Day 19 Santa Cruz de La Palma, Spain

Also known as ‘La Isla Bonita' (the beautiful island), La Palma is typified by lush forests of pine, laurel and fern which contrast with the rugged splendour of the gigantic Taburiente crater. The island is dotted with attractive villages, which are a delight to discover, and the capital Santa Cruz also makes for an interesting day of exploration. Perched on the edge of the volcanic crater of La Caldereta, Santa Cruz comfortably blends modern architecture with old colonial buildings. Perhaps visit the fascinating Natural History Museum, stroll around the historic quarters and the Plaza de Espana or travel a few miles outside the city to the exquisite Church of Our Lady. If you enjoy shopping, you can find reasonably priced silver jewellery, leather goods and beautifully embroidered clothes, tablecloths and napkins, a speciality of the Canary Islands.

Day 26 San Juan (Puerto Rico), Puerto Rico

If you associate Puerto Rico's capital with the colonial streets of Old San Juan, then you know only part of the picture. San Juan is a major metropolis, radiating out from the bay on the Atlantic Ocean that was discovered by Juan Ponce de León. More than a third of the island's nearly 4 million citizens proudly call themselves sanjuaneros. The city may be rooted in the past, but it has its eye on the future. Locals go about their business surrounded by colonial architecture and towering modern structures.By 1508 the explorer Juan Ponce de León had established a colony in an area now known as Caparra, southeast of present-day San Juan. He later moved the settlement north to a more hospitable peninsular location. In 1521, after he became the first colonial governor, Ponce de León switched the name of the island—which was then called San Juan Bautista in honor of St. John the Baptist—with that of the settlement of Puerto Rico ("rich port").Defended by the imposing Castillo San Felipe del Morro (El Morro) and Castillo San Cristóbal, Puerto Rico's administrative and population center remained firmly in Spain's hands until 1898, when it came under U.S. control after the Spanish-American War. Centuries of Spanish rule left an indelible imprint on the city, particularly in the walled area now known as Old San Juan. The area is filled with cobblestone streets and brightly painted, colonial-era structures, and its fortifications have been designated a UNESCO World Heritage Site.Old San Juan is a monument to the past, but most of the rest of the city is planted firmly in the 21st century and draws migrants island-wide and from farther afield to jobs in its businesses and industries. The city captivates residents and visitors alike with its vibrant lifestyle as well as its balmy beaches, pulsing nightclubs, globe-spanning restaurants, and world-class museums. Once you set foot in this city, you may never want to leave.

Day 29 Miami, Florida, United States

Miami is one of the world's most popular holiday spots. It has so much to offer; from its countless beach areas, to culture and museums, from spa and shopping days out, to endless cuban restaurants and cafes. Miami is a multicultural city that has something to offer to everyone.

Day 31 Georgetown, Grand Cayman, Cayman Islands

Begin exploring the capital by strolling along the waterfront Harbour Drive to Elmslie Memorial United Church, named after the first Presbyterian missionary to serve in Cayman. Its vaulted ceiling, wooden arches, and sedate nave reflect the religious nature of island residents. In front of the court building, in the center of town, names of influential Caymanians are inscribed on the Wall of History, which commemorates the islands' quincentennial in 2003. Across the street is the Cayman Islands Legislative Assembly Building, next door to the 1919 Peace Memorial Building. In the middle of the financial district is the General Post Office, built in 1939. Let the kids pet the big blue iguana statues.

Day 33 Cartagena, Colombia

Cartagena's magnificent city walls and fortresses, now a UNESCO World Heritage Site, enclose a well-restored historic center (the Cuidad Amurallada, or walled city) with plazas, churches, museums, and shops that have made it a lively coastal vacation spot for South Americans and others. New hotels and restaurants make the walled city a desirable place to stay, and the formerly down-at-the-heels Getsemaní neighborhood attracts those seeking a bohemian buzz. The historic center is a small section of Cartagena; many hotels are in the Bocagrande district, an elongated peninsula where high-rise hotels overlook a long, gray-sand beach.When it was founded in 1533 by Spanish conquistador Pedro de Heredia, Cartagena was the only port on the South American mainland. Gold and silver looted from indigenous peoples passed through here en route to Spain and attracted pirates, including Sir Francis Drake, who in 1586 torched 200 buildings. Cartagena's walls protected the city's riches as well as the New World's most important African slave market.

Day 36 Puntarenas, Costa Rica

This town is not on the Nicoya Peninsula, but rather on Costa Rica's mainland. It is best known as a cruise-ship port and launching pad for ferries heading southeast to the coast of the Nicoya Peninsula and for cruises sailing out on the Gulf of Nicoya. Puntarenas is also a major fishing port with a lively fish market. The town's reputation suffers from the unimpressive parts you see from your car as you roll through town on the way to the ferry dock. But the town has a lot of character off the main drag, thanks to its illustrious past as an affluent port town and principal vacation spot for San José's wealthy, who arrived by train in the last century. Once the port was moved and roads opened to other beaches, Puntarenas's economy crashed, but it's making a comeback. Sitting on a narrow spit of sand—punta de arenas literally means "point of sand"—that protrudes into the Gulf of Nicoya, the town boasts a beautifully groomed, wide Blue Flag beach with views of the Nicoya Peninsula and spectacular sunsets, along with a public swimming pool, the San Lucas Beach Club, and a marine-life museum. Ticos arrive by bus and car to enjoy the beach and stroll the Paseo de los Turistas, a beachfront promenade lined with tree-shaded concrete benches and seafood restaurants. Crowds of locals, called porteños, cruise by on bicycles, the town's most popular form of transport.

Day 38 Corinto, Nicaragua

Day 39 Puerto Quetzal, Guatemala

Puerto Quetzal is Guatemala's largest Pacific Ocean port. It is important for both cargo traffic and as a stop-off point for cruise liners

Day 41 Acapulco, Mexico

Acapulco is a major seaport on the scenic Pacific coast of Mexico, located on a deep semi-circular bay with sandy beaches and blue waters. It was a popular destination for many movie stars during the Golden Age of Hollywood, including Elvis Presley and Elizabeth Taylor.

Day 43 Puerto Vallarta, Mexico

Puerto Vallarta is a resort town on Mexico's Pacific coast, in Jalisco state. It is known for its beaches, water sports and nightlife scene. Its cobblestone center is home to the ornate Nuestra Señora de Guadalupe church, boutique shops and a range of restaurants and bars. El Malecón is a beachside promenade with contemporary sculptures, as well as bars, lounges and nightclubs.

Day 46 Los Angeles, California, United States

Home of the famous Hollywood sign and Walk of Fame, Los Angeles is the place to visit for anyone interested in film and television and hoping to get a glimpse at some famous actors and artists. Stroll down the Walk and enjoy the glamorous atmosphere and famous surroundings, or take a break on the Santa Monica pier and watch the sun set on the sea.