Day 1 Civitavecchia, Italy

Italy's vibrant capital lives in the present, but no other city on earth evokes its past so powerfully. For over 2,500 years, emperors, popes, artists, and common citizens have left their mark here. Archaeological remains from ancient Rome, art-stuffed churches, and the treasures of Vatican City vie for your attention, but Rome is also a wonderful place to practice the Italian-perfected il dolce far niente, the sweet art of idleness. Your most memorable experiences may include sitting at a caffè in the Campo de' Fiori or strolling in a beguiling piazza.

Day 2 Messina, Italy

Home to the Museo Regionale of Messina, known for featuring two of Caravaggio's paintings, the city is also famous for having been the capital of the ancient kingdom of Sicily.

Day 4 Rhodes, Greece

Early travelers described Rhodes as a town of two parts: a castle or high town (Collachium) and a lower city. Today Rhodes town—sometimes referred to as Ródos town—is still a city of two parts: the Old Town, a UNESCO World Heritage site that incorporates the high town and lower city, and the modern metropolis, or New Town, spreading away from the walls that encircle the Old Town. The narrow streets of the Old Town are for the most part closed to cars and are lined with Orthodox and Catholic churches, Turkish houses (some of which follow the ancient orthogonal plan), and medieval public buildings with exterior staircases and facades elegantly constructed of well-cut limestone from Lindos. Careful reconstruction in recent years has enhanced the harmonious effect.

Day 5 Limassol, Cyprus

A major commercial port, cruise ship port of call, and wine-making center on the south coast, Limassol, 75 km (47 miles) from Nicosia, is a bustling, cosmopolitan town, with some of the liveliest nightlife on the island. Luxury hotels, apartments, and guesthouses stretch along 12 km (7 miles) of seafront, with the most luxurious ones just to the north of town. In the center, the elegant, modern shops of Makarios Avenue (where you'll mainly find clothes and shoes) contrast with those of pedestrian-only Agiou Andreou in the old part of town, where local handicrafts such as lace, embroidery, and basketware prevail; make sure you avoid shopping on Wednesday and Saturday afternoons, when many shops close at 2 pm. A luxurious marina that will hold 650 yachts as well as house apartments, shops, and restaurants should further boost the town's lively appeal.

Day 6 Alexandria, Egypt

Founded by Alexander the Great, Alexandria was Egypt's capital for over 1,000 years. Now, it is visited by tourists looking to enjoy some diving and those interested in the Great Library, one of the Seven Wonders of the Ancient World.

Day 9 Sharm El Sheikh, Egypt

The port and town of Sharm-el-Sheikh lies near the southernmost tip of the Sinai Peninsula where the Straits of Tiran meet the Gulf of Aqaba. With its strategic position, the Sinai posed a desirable target for various rulers over the centuries. In recent times, the last battle for the Sinai was fought between Egypt and Israel from 1967 to 1979, ending with a peace treaty signed in Washington, D.C. Since the withdrawal of the Israelis, more and more Egyptians have settled in the Sinai, taking advantage of the booming tourist trade. However, vast interior regions are still sparsely populated. Many Bedouins have been affected by the advent of the 21st century, which is rapidly changing their age-old customs and nomadic lifestyle. As tourism and hotel projects continue to spring up along the Sinai coast, contact with Bedouins not involved in tourism is becoming increasingly rare. Once their nomadic life kept them on the move with their tents; today many Bedouins cultivate grain, vegetables and dates in addition to catering to the tourists. Sharm-el-Sheikh was initially developed by the Israelis during the Sinai occupation. Na'ama Bay, a short drive from the port, has grown from virtually nothing into a sizeable resort since the early 1980s. Between the two towns, a string of hotels line a once-untouched coastline. Resort hotels offer great opportunities for swimming, snorkelling and scuba diving. Glass bottom boat trips are available for those preferring to view the exotic marine life of the Red Sea without getting their feet wet.

Day 10 Safaga, Egypt

Port Safago has been undergoing a transformation, slowly metamorphosing into a holiday rsort. Like other cities on the Red Sea, the commercial port town sits close to great offshore dive sites. Unlike others, however, tourist development hasn't taken off in a meaningful way. But if the mass tourism in Hurghada is a turnoff, Safaga offers a small-scale and much more low-key alternative, though the best dive sites can still be seen on a day trip from Hurghada. Safaga is also the closest beach resort to Luxor and the Valley of the Kings, which lies 200 km (124 mi) to the southwest; when cruise ships offer land excursions to Luxor, they often do so through Safaga.

Day 18 Port Victoria, Seychelles

Day 21 Port Louis, Mauritius

Mauritius' largest city, Port Louis is a vibrant and exciting place whose culture is a mix of African, Chinese and Indian influences. There are activities and sights to keep you busy and explore the different aspects of the city.

Day 22 Possession, Réunion

Day 26 Durban, South Africa

Durban, a glistening jewel on the south-east coast of Africa, is the third largest city in South Africa and the major city of KwaZulu-Natal. It has been a centre of sea trade since before colonisation and now has a flourishing artistic centre, which perfectly complements the vibrant markets and rich cultures of the city. Durban's port is a natural half-moon harbour lined with white sand and azure water, punctuated by the port's many piers which reach into the water like the leaves of a fan. The beaches of Durban's famous Golden Mile stretch along the harbour and are popular all year round, as travellers and locals alike enjoy Durban's warm, humid summers and mild, dry winters.